Fun, frank and in turn emotional and heart-warming, the chat show's guests will delight with their humorous, intimate and often surprising anecdotes.
Plus, Jonathan will welcome more of the hottest musical acts, performing their latest tracks live in the studio.
Jonathan is joined by double Strictly Come Dancing champion Oti Mabuse, BAFTA Award winning star of This Country Daisy May Cooper, the always hilarious Jimmy Carr, father and son duo Martin and Roman Kemp, plus international multiplatinum selling artist James Arthur will be performing in the studio.
The Jonathan Ross Show returns Saturday 10th April at 9:35pm on ITV.